With its verdant backdrop, high-altitude location—a dizzying 11,150 feet (3,400 meters) above sea level—and rich indigenous culture, Cusco is one of the most enchanting South American cities. Perhaps best known as the gateway to Machu Picchu, this city was the sacred capital of the Incas until the Spanish Conquest and is the grand finish to the legendary Inca Trail. Around one hour and 30 minutes from Cusco, the Sacred Valley of the ancient Incas boasts a wealth of archaeological wonders, traditional market villages, and mesmerizing views, while the Salkantay and Lares treks are two of the country’s most worthwhile long-distance hikes. And there are plenty of things to do in Cusco itself, with its beautiful colonial buildings, buzzing marketplace, and traditional and neo-Andean restaurants.