Occupying a prime position on Colombia’s Caribbean Coast, Cartagena de Indias is where the culture of South America and the Caribbean collide. The seaside city is a bold and beautiful banquet for the senses—brightly-colored buildings, bougainvillea-clad balconies, fragrant street food stalls, bustling markets, and party-fuelled chiva buses all contribute to the cultural heritage of the UNESCO-listed Old Town of this one-of-a-kind place—and that’s just in the center. Travel further afield for some of the best things to do in Cartagena, including volcanic mud baths, the paradise Rosario Islands (Islas del Rosario) in the Caribbean Sea, and spectacular national parks.