By taking a day trip from Barcelona to Madrid, you’ll get to experience Spain’s two principal cities without the hassle of logistics—and all in just one day. Most itineraries typically include round-trip, high-speed train travel and guided explorations of top Madrid attractions such as the renowned Prado Museum, home to masterpieces by Goya and Velázquez, as well as the Royal Palace of Madrid. You’ll also enjoy time to stroll down the Gran Vía shopping avenue, and visit the Mercado San Miguel.